專任-系統生物與生物資訊組   首頁 師資介紹 專任-系統生物與生物資訊組
馬念涵 教授 Nian-Han Ma
從聘系所:
專線電話:03-4227151轉36112
傳真電話:
學經歷

學歷:

   博士 美國耶魯大學

   碩士 國立臺灣大學

   學士 國立中興大學


經歷:

   紀念史隆凱特林癌症中心

   美國耶魯大學

   國立中央大學 系統生物與生物資訊研究所 助理教授

   國立中央大學 系統生物與生物資訊研究所 副教授


現職:

   國立中央大學 系統生物與生物資訊研究所 教授

論文著作區


(Ma lab members in bold: graduate students#; postdocs†)

1.     Thi Nguyen M#, Lin CH†, Liu SM#, Miyashita A, Ihn H, Lin H, Ng CH, Tsai JC#, Chen MH, Tsai MS, Lin IY#, Liu SC, Li LY, Fukushima S *, Lu J*, Ma N*, miR-524-5p reduces the progression of the BRAF inhibitor-resistant melanoma, Neoplasia, 2020, 22(12):789-799

2.     Cheng C, Yang SC, Lai CY, Wang CK, Chang CF, Lin CY, Chen WJ, Lin PY, Wu HC, Ma N, Lu FL, Lu J, CXCL14 Maintains hESC Self-Renewal through Binding to IGF-1R and Activation of the IGF-1R Pathway, Cells, 2020 Jul 16;9(7):1706. doi: 10.3390/cells9071706.

3.     Chen CL#, Lin CH†, Li AL#, Huang CC, Shen BY, Chiang YU#Fang PL#, Chang HC, Li, KL, Yang WC, Horng JT*, Ma N*, Plasma MicroRNA Profile is a Biomarker Associated with Urothelial Carcinoma in Chronic Hemodialysis Patients, Am J physiol Renal physiol, 2019,316(6):F1094-F1102 [IF=3.323, R/C=16/80, Urology & Nephrology]

4.     Lin IY#, Chiou YS, Wu LC, Tsai CY, Chen CT, Chuang WC, Lee MC, Lin CC, Lin TT#, Chen SC, Pan MH*, Ma N*, CCM111 prevents hepatic fibrosis via cooperative inhibition of TGF-β, Wnt and STAT3 signaling pathways, Journal of Food And Drug Analysis, 2019, 27(1):184-194 [IF=4.176, R/C=13/135, Food Science & Technology]

5.     Li AL#, Chung TS, Chan YN#Chen CL#, Lin SC, Chiang YU#Lin CH#, Chen CC, Ma N*, microRNA expression pattern as an ancillary prognostic signature for radiotherapy, Journal of Translational medicine, 2018,16 (1): 341 [IF=4.098, R/C=41/136, Medicine, Research & Experimental]

6.     Liu SM#Lin CH†, Lu J, Lin IY#, Tsai MS, Chen MH and Ma N*, miR-596 modulates melanoma growth by regulating cell survival and death, Journal of Investigative Dermatology, 2018, 138(4), 911-921 [IF=6.290, R/C=4/66, Dermatology]

7.     Chen WY, Ma N, Li TL, Su LJ, Chang YH, MicroRNA in situ hybridization with phosphate-methylated oligonucleotides (nDNA) probe, New Biotechology,2018, 44, S147 (IF=3.739, R/C= (Q1), Biotechology)

8.     Lin IY#, Pan MH, Lai CS, Lin TT#, Chen CT, Chung TS, Chen CL, Lin CH†, Chuang WC, Lee MC, Lin CC, Ma N*, CCM111, the water extract of Antrodia cinnamomea, regulates immune-related activity through STAT3 and NF-κB pathways, Scientific Reports, 2017, 7(1):4862. [IF=4.122, R/C=12/64, Multidisciplinary Sciences]

9.     Hsu C-L, Chung F-H, Chen C-H, Hsu T-T, Liu S-M#, Chung D-S, Hsu Y-F, Chen CL#Ma N* and Lee H-C*, Genotypes of cancer stem cells characterized by epithelial-to-mesenchymal transition and proliferation related functions, (* Co-corresponding Author), Scientific Reports, 2016, 6:32523. [IF=4.259, R/C=10/64, Multidisciplinary Sciences]

10.   Yen C-I, Liu SM#, Lo W-S , Wu J-W, Liu Y-H, Chein R-J, Yang R, Ma N* and Shieh F-K*, Cytotoxicity of Postmodified Zeolitic-Imidazolate Framework-90 (ZIF-90) Nanocrystals: Correlation between Functionality and Toxicity, (* Co-corresponding Author), Chemistry - A European Journal, 2016, 22(9):2925-9 [IF=5.317, R/C=29/166, Chemistry, Multidisciplinary]

11.   Lin S-J, Wu S-W, Chou Y-C, Lin J-H, Huang Y-C, Chen M-R, Ma N* and Tsai C-H*, Novel expression and regulation of TIMP-1 in Epstein Barr virus-infected cells and its impact on cell survival (* Co-corresponding Author), Virology2015,481:24-3333 [IF=3.367, R/C=13/35, Virology]

12.   Wu C-C, Wu H-J, Wang C-H, Lin C-H, Hsu S-C, Chen Y-R, Hsiao M, Schuyler S C, Lu FL, Ma N, and Lu J, Akt suppresses DLK for maintaining self-renewal of mouse embryonic stem cells, Cell Cycle, 2015,14(8), 1207-1217 [IF=3.952, R/C=68/187, Cell Biology]

13.   Ma N#, Lai C-H#, Chung C-H, Yang J-M, Hsu K-Cheng, Chen C-Y, Chung T-S, Li S, Ho C-T, Pan M-H*, 5-Demethyl tangeretin is more potent than tangeretin in inhibiting dimethylbenz(a) anthracene (DMBA)12-O-tetradecanoyl phorbol-13-acetate (TPA)-induced skin tumorigenesis, (# Co-First Author), Journal of Functional Foods, 2014, 11:528-537 [IF: 3.574; 7/123; Food Science & Technology]

14.   Liu SM#, Lu J, Lee, HC, Chung FH, and Ma N*, miR-524-5p suppresses growth of oncogenic BRAF melanoma by targeting BRAF and ERK2, Oncotarget, 2014, 5(19):9444-59[IF=5.008; R/C= 36/213, Oncology]

15.   Lo W-S, Liu SM#, Wang S-C, Lin H-P, Ma N*, Huang H-Yand Shieh F-K*, A green and facile approach to obtain 100 nm zeolitic imidazolate framework-90 (ZIF-90) particles via leveraging viscosity effects (* Co-corresponding Author), RSC Advances2014, 4:52883-86 [IF=3.289, R/C=49/163, chemistry, multidisciplinary]

16.   Lin CH, Wu JC, Chiou BH, Chen CH, Ma N, Chang CY, Tsen YK and Chen SC, MicroRNA regulation of DNA repair gene expression in 4-aminobiphenyl-treated HepG2 cells, Toxicology, 2014, 322:69-77 [IF=3.817, R/C=13/ 90,Toxicology]

17.   Huang HN, Chen SY, Hwang SM, Yu CC, Su M-W, Mai W, Wang, HW, Cheng WC, Schuyler SC, Ma N, Lu FL, Lu J, miR-200c and GATA binding protein 4 regulate human embryonic stem cell renewal and differentiation, Stem Cell Research, 2014,12(2):338-353 [IF=3.892, R/C=30/161, biotechnology & applied microbiology]

18.   Chung, FH, Chiang, YR, Tseng, AL, Sung, YC, Lu, J, Huang, MC, Ma, N*, Lee, HC*, Functional Module Connectivity Map (FMCM): A Framework for Searching Repurposed Drug Compounds for Systems Treatment of Cancer and an application to Colorectal Adenocarcinoma (* Co-corresponding Author), Plos One, 2014, 9(1): e86299.[ R/C=9/57, Multidisciplinary Sciences]


研究計畫區
專利區

1.  Ma N, Chung TS, Chan YN, Chen CL, Lee AL, Analyzer and analytical method for predicting the prognosis of cancer radiotherapy, Taiwan #I614629 2018/2-2037/2,

US# 15/691,730(applying) ; China#201710581670.0 (applying)

2.  Ma N, Chen CL, Lin CH, Li AL, Huang, CC, Chang CH, Detection Kit And Detection Method For Urothelial Carcinoma, (applying): Taiwan, 107140464; US and China #201910126024.4

3.  Ma N, Huang, CC, Chang CH Chen CL, Li AL Method For Estimating A Risk For A Subject Suffering From Urothelial Carcinoma And Kit Thereof, ((applying), Taiwan, 108103917, US and China

4.  Ma N, Lin CH, Su HH, Chen CH, Glucose dehydrogenase and method for producing the dehydrogenase, US#62/192,074