專任教師-生物醫學工程組   首頁 師資介紹 專任教師-生物醫學工程組
林澂 助理教授 Chen Lin
從聘系所:
專線電話:03-4227151轉27756
傳真電話:
E-mail :clin@ncu.edu.tw
學經歷
Education
National Central University, Taiwan
Ph.D. in Institute of Systems Biology and Bioinformatics
September, 2008 ~ July, 2012
National Yang Ming University, Taiwan
M.S.of Institute of Physiology
September, 2002 ~ June, 2004


Dissertation

Ph.D. Degree
Title: “Application of Hilbert-Huang Transform in Exploring the Nonlinear Characteristics of Biomedical Signals”
Advisor: Prof. Norden Er Huang

M.S. Degree
Title: ”Short-term and long-term outcome assessment in surgical critically-ill patients-linear and nonlinear analyses of heart rate dynamics”
Advisor: Prof. Yu Ru Kou

Academic and professional experiences
Assistant Research Fellow
Center for Adaptive Data Analysis, National Central University
Feb, 2014~
Taiwanese Team of Qualcomm Tricorder XPRIZE Competition (Co-PI in Vital Sign Group)
Sep, 2013~
Post-Doctoral Fellow
Department of Behavioral Science and Psychiatry, Stanford University
Sep, 2012~Sep, 2013
Research assistant
Surgical intensive care unit,
Taipei Veterans General Hospital
April, 2006~June, 2008
Second lieutenant
Army, Taiwan
October, 2004~March, 2006
論文著作區

l   Y.-H. Lin, M.-T. Lo, X.-M. Wu, C.-S. Hung, Y.-L. Ho, K.-D. Wu, C. Lin#, V.-C. Wu, M. Stowasser, C.-K. Peng and the TAIPAI Study Group “Adrenalectomy reverses the impaired heart rhythm complexity in patients with primary aldosteronism” Scientific Reports (Accepted; #corresponding author IF:5.078; 5/55)

l  Y.-H. Lin*, C. Lin*, M.-T. Lo, H.-J. Lin, Y.-W. Wu, R.-B. Hsu, C.-L. Chao, H.-C. Hsu, P.-C. Wang, V.-C. Wu, S.-S. Wang, C.-M. Lee, K.-L. Chien, Y.-L. Ho, M.-F. Chen and C. K. Peng The relation between aminoterminal propeptide of type III procollagen and heart rate variability parameters in heart failure patients: a potential serum marker to evaluate cardiac autonomic control and sudden cardiac death, Clin Chem Lab Med, 2010 Dec, 48(12):1821-7. (* Equal first author; IF:2.9, 5/31)

l  C. Lin and M.-T Lo “Recent Progresses in Sleep Monitoring”, Formosan Journal of Medicine, 2014 Mar; 18(2): 172-180 

l  Y. Lin, C. Lin, I.-W Sun, C.-C. Hsu, C.-K Fang, M.-T. Lo, H.-C. Huang, and S.-I. Liu “Resting Respiratory Sinus Arrhythmia is Related to Longer Hospitalization in Mood-disordered Repetitive Suicide Attempters” World J of Biol Psychia (Accepted; IF:4.22, 26/136)

l  P.-H. Tsai, C. Lin, J. Tsao, P.-F. Lin, P.-C. Wang, N.E. Huang, M.-T. Lo, Empirical mode decomposition based detrended sample entropy in electroencephalography for Alzheimer's disease. J Neurosci Methods, 2012 Sep 30; 210(2):230-7. (IF:1.9, 182/252)

l  Y.-L. Ho, C. Lin, Y.-H. Lin and M.-T. Lo, The prognostic value of non-linear analysis of heart rate variability in patients with congestive heart failure- A pilot study of multiscale entropy, PLoS One, 2011 Apr, 6(4), e18699. (IF:3.534; 8/55)

l  H.-K. Yuan, C. Lin, P.-H. Tsai, F.-C. Chang, K.-P. Lin, H.-H. Hu, M.-C. Su and M.-T. Lo, Acute increase of complexity in the neurocardiovascular dynamics following carotid stenting, Acta Neurol Scand, 2011 Mar, 123(3):187-9 (IF:2.4, 87/194)

l   J.-R. Yeh, L.-C. Hsu, C. Lin, F.-L. Chang and M.-T. Lo*, “Nonlinear Analysis of Sensory Organization Test for Subjects with Unilateral Vestibular Dysfunction”, PloS One, 2014 Mar; 9(3): e91230 (IF:3.534; 8/55)

l  M.-T Lo, Y.-C. Chang, C. Lin, Vincent H.-W. Young, Y.-H. Lin, Y.-L. Ho, C.-K. Peng, K. Hu “Outlier-resilient complexity analysis of heartbeat dynamics” Scientific Reports (Accepted; IF:5.078; 5/55)

l  M. Cao, C. Guilleminault, C. Lin, Central Sleep Apnea: Effects on Stroke Volume in Heart Failure, Am J Respir Crit Care Med, 2013 Feb, 187(4):340-1. (Letter to Editor; IF:11.9, 1/54)

l  Y.-J. Lin, M.-T. Lo, C. Lin, S.-L. Chang, L.-W. Lo, Y.-H. Hu, W.-H. Hsieh, H.-Y Chang, W.-Y Lin, F.-P. Chung, J. Liao, Y.-Y Chen, D. Hanafy, N.E. Huang, S.-A. Chen, Prevalence, Characteristics, Mapping, and Catheter Ablation of Potential Rotors in Non-Paroxysmal Atrial Fibrillation Circ Arrhythm Electrophysiol, 2013  Oct; 6(5):851-8 (IF:5.4, 18/125)

l  Y.-J. Lin, M.-T. Lo, C. Lin, S.-L. Chang, L.-W. Lo, Y.-H. Hu, T.-F. Chao, C.-H. Li, Y.-C Chang, W.-H. Hsieh, F.-P. Chung, H.-M. Tsao, H.-Y Chang, N.E. Huang, S.-A. Chen, Nonlinear analysis of fibrillatory electrogram similarity to optimize the detection of complex fractionated electrograms during persistent atrial fibrillation. J Cardiovasc Electrophysiol. 2013 Mar; 24(3): 280-9. (IF:3.2, 42/125)

l  Y.-H. Lin, H.-C. Huang, Y.-C. Chang, C. Lin, M.-T. Lo, L.-Y. D. Liu, P.-R. Tsai, Y.-S. Chen, W.-J. Ko, Y.-L. Ho, M.-F. Chen, C.-K. Peng and T. G. Buchman, “Multi-scale Symbolic Entropy Analysis Provides Prognostic Prediction in Patients Receiving Extracorporeal Life Support”, Critical Care, 2014 Oct 24; 18(5): 548 (IF:5.035; 5/27)

l  Y.-J. Lin, K. Suenari, M.-T Lo, C. Lin, W.-H Hsieh, S.-L Chang, L.-W Lo, Y.-F Hu, C.-C Cheng, W.-S. Lin, Y. Kihara, T.-F. Chao, B. Hartono, T.-J Wu, N. E. Huang, S.-A. Chen, A Novel Assessment of the Temporal Variation in the Fractionated Electrograms Using a Histogram Analysis of the Local Fractionation Interval in Persistent Atrial Fibrillation Patients, Circ Arrhythm Electrophysio, 2012 Oct, 5(5):949-56. (IF:5.4, 18/125)

l   P.-F. Lin, J. Tsao, M.-T. Lo, C. Lin, Y.-C. Chang “Symbolic Entropy of the Amplitude rather than the Instantaneous Frequency of EEG Varies in Dementia”, Entropy, 2015 Jan; 17(2): 560-579  (IF: 1.564; 29/78)

l  L.-C. Wu, H.-H. Chen, J.-T. Horng, C. Lin, N.E. Huang, Y.-C. Cheng, and K.-F. Cheng, A Novel Preprocessing Method Using Hilbert Huang Transform for MALDI-TOF and SELDI-TOF Mass Spectrometry Data, PLoS One, 2010 Aug,5(8):e12493. (IF:3.534; 8/55)

l  L.-Y. Lin, M.-T. Lo, P. C.-I. Ko, C. Lin, W.-C. Chiang, Y.-B. Liu, M. H.-M. Ma, J.-L. Lin and W.-J. Chen, Detrended Fluctuation Analysis Predicts Successful Defibrillation for Out-of-Hospital Ventricular Fibrillation Cardiac Arrest, Resuscitation, 2010 Jan, 81(3): 297-301. (IF: 3.960; 2/25)

l  M.-T. Lo, P.-H. Tsai, P.-F. Lin, C. Lin and Y.-L. Hsin, The Nonlinear and Nonstationary Prosperities in EEG Signals: Probing the Complex Fluctuations by Hilbert-Huang Transform, Advances in Adaptive Data Analysis, 2009 Jul, 1(3):461-482.

l  P.-F. Lin, M.-T. Lo, J. Tsao, Y.-C. Chang, C. Lin and Y.-L. Ho, “Correlations between the Signal Complexity of Cerebral and Cardiac Electrical Activity: A Multiscale Entropy Analysis”, PloS One, 2014 Feb; 9(2): e87798 (IF:3.534; 8/55)

l  M.-T. Lo, L.-Y. Lin, W.-H. Hsieh, P.-C. Ko, Y.-B. Liu, C. Lin, Y.-C. Chang, C.-Y. Wang, V.-H. Young, W.-C. Chiang, J.-L. Lin, W.-J. Chen, M.-H Ma. “A New Method to Estimate the Amplitude Spectrum Analysis of Ventricular Fibrillation during Cardiopulmonary”, Resuscitation, 2013 Nov; 84(11): 1505–1511 (IF: 3.960; 2/25)

l   T.-C. Tuan, M.-T. Lo, Y.-J. Lin, W.-H. Hsieh, C. Lin, N. E. Huang, L.-W. Lo, T.-F. Chao, J. Liao, Y.-C. Hsieh, T.-J. Wu, S.-A. Chen, “The Use of Signal Analyses of Ventricular Tachycardia Electrograms to Predict the Response of Anti-tachycardia Pacing in Patients with Implantable Cardioverter-defibrillators”, Journal of Cardiovascular Electrophysiology, 2014 Apr; 25(4): 411-417 (IF: 3.234; 42/125)

l  Y.-C Liu, C.-S Hung, Y.-W Wu, Y.-C. Lee, Y.-H. Lin, C. Lin, M.-T. Lo, C.-C Chan, H.-P Ma, Y.-L. Ho, C.-H. Chen, Influence of non-alcoholic fatty liver disease on autonomic changes evaluated by the time domain, frequency domain, and symbolic dynamics of heart rate variability. PLoS One, 2013 Apr 23; 8(4): e61803 (IF:3.534; 8/55)

l  L.-Y. Lin, M.-T. Lo, P. C.-I. Ko, W.-C. Chiang, C. Lin, K.-H Hsiung, J.-L. Lin , W.-J. Chen and M. H.-M. Ma, A new way to analyze resuscitation quality by reviewing automatic external defibrillator data, Resuscitation, 2012 Feb, 83(2):171-6. (IF: 3.960; 2/25)

l  Y.-C. Chang, L.-K. Huon, V.-T. Pham, Y.-J. Chen, S.-F. Jiang, T. T.-F. Shih, T.-T. Tran, Y.-H. Wang, C. Lin, J. Tsao, M.-T. Lo and P-C Wang, "Synchronized imaging and acoustic analysis of the upper airway in patients with sleep-disordered breathing", Physiological Measurement, 2014 Dec; 35(12): 2501-12 (IF: 1.617; 37/76)

Conference

A.    Invited Speaker

·             “Probing the time-frequency representation of nonlinear and nonstationary signals by Hilbert-Huang transform”, The 2014 Annual meeting of Society of Exploration Geophysicists, Denver, U.S. (2014)

·             “The Use of Signal Analyses of Ventricular Tachycardia Electrograms to Predict the Response of Anti-tachycardia Pacing in Patients with Implantable Cardioverter-Defibrillators” 2015 THRS 1st International Forum of Ventricular Arrhythmia, Taipei, Taiwan (2015)

B.     Oral Presentation

l   “Changes of Electroencephalogram with flow limitation during NREM stage II sleep in patients with upper airway resistance syndrome evaluated by a novel respiratory cycle-based analysis.” 2014 Annual Meeting of American Academy of Sleep Medicine, Minneapolis, USA (2014)

l   “Different activation of autonomic nervous system with flow limitation”, The 2013 World Congress on Sleep Medicine, Valencia, Spain (2013)

l   “A new way to analyze resuscitation quality by reviewing automatic external defibrillation data”, The 3rd International Conference on Hilbert-Huang Transform, Qingdao, China (2011)

C.    Poster Presentation

l   C. Lin, M.-T. Lo, S.-Y. Lee, MD, C. Guilleminault, Flow limitation and respiratory efforts during Stage2 NREM sleep. 2013 annual meeting of American Academy of Sleep Medicine, Baltimore, USA (2013)

l   C. Lin, P.C.-I Ko, M-T. Lo, W.-C. Chiang, W.-H. Hsieh, L.-Y. Lin, C.-H. Huang, J.-L Lin, W.-J. Chen, M.H.-M. Ma, Detection of Ventricular Fibrillation With Continuing Chest Compression Using Adaptive Least Mean-Square Estimation of the Cardiopulmonary Resuscitation Artifact and Removal of the Artifacts. 2013 Resuscitation Science Symposium, Los Angeles, USA (2013)

研究計畫區

·             2014-2017       Realization of a wearable device for biomarker detection and cloud computation based feedback (Subproject 3 :  Exploiting biomarkers of physiological signals recorded from wearable devices by using adaptive data analysis) 103-2218-E-008-006-   

·             2014-2016   Industrial Technology Development Program- Smart Health Care Wearable Devices with Soft Screen (Subproject: Developing wearable vital sign monitoring and extracting the precursors of cardiovascular diseases)

專利區

System and method for improved complex fractionated electrogram ablation”, US 13558616 Jan 30,2014

System and method for predicting successful defibrillation for ventricular fibrillation cardiac arrest US 8380305 Feb 19, 2013